I’ve always loved to write stories, and still do. Martin Turner 1 , Manuel D Díaz-Muñoz 2 3 Affiliations 1 Laboratory of Lymphocyte Signaling and Development, The Babraham Institute, Cambridge, UK. This would have to be handing in my final bound PhD thesis into the registry office in Cambridge- I was dead chuffed! Adventurous, creative and inquisitive. I got to travel and spend a year in France researching CBP/p300 in breast cancer, which was very rewarding. We investigate the role of a family of enzymes called PI3K and how they affect our immune responses to infections and cancer. In science there is no real typical day – there is always something new to discover! Head of Lymphocyte Signalling, Babraham Institute, Cambridge. I studied Natural Sciences (which is just a mixture of whichever sciences I fancied) at Cambridge University – I specialised in Biochemistry. My father, who sadly passed away from lung cancer. It might be a bit surprising when I say it was almost a given thing when I was in school! I'm working as part of a team that studies the proteins that activate Rac, switching it into its 'on' state.
We are trying to understand the mechanisms required for antibody recombination - how this huge piece of DNA with hundreds of genes is unwound and changes shape to bring all the genes together so they can all be cut and pasted together to make millions of different antibody sequences. I went to the University of York studying Genetics. 8 Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge, United Kingdom martin.turner@babraham.ac.uk p.katsikis@erasmusmc.nl. I wasn’t too fussed though – I liked the subjects. I am not sure, but I would perhaps be doing something completely different like working in a bakery or patisserie. I study the relationship between pathogens and their host.
Mostly my days involve a lot of laughter, fun and hard work! It is the foundation of originality. Answering a question. Motivated, creative and innovative.
physiology and homeostatic control, and to promote effective translation of basic bioscience to enable And I will be more than happy if, in the long run, my work can help increase our understanding of how living organisms work, potentially paving the way for improved medical treatments. Recent work by his group seeks to understand how RNA-processing mechanisms control the development and function of B and T lymphocytes. BACKGROUND: Members of the ZFP36 family of RNA-binding proteins regulate gene expression post-transcriptionally by binding to AU-rich elements in the 3'UTR of mRNA and stimulating mRNA degradation. The Babraham Institute is an international leader in research focusing on basic cell and molecular biology with an emphasis on I didn’t do A Levels exactly – I had an equivalent exam in Malaysia (which is where I grew up), and I took Biology, Chemistry, Mathematics and English Literature, as well as a compulsory General Paper. Polypyrimidine Tract Binding Protein 1 (PTBP1) is a RNA-binding protein (RBP) expressed throughout B cell development. Tel.+44 (0)1223 496000
Chemistry, mathematics and arts.
By the end of my master degree I was able to answer one of the several questions that scientists pursue. My lab seeks an understanding of these mechanisms in the context of lymphocyte development and activation. A typical day is spent mainly in the lab performing experiments and processing samples, as well as analysing and interpreting the data- ready to plan the next experiment web browser if you wish but then our site may not work correctly. Understanding how RNA binding proteins regulate immune cell function
When doing experiments, I usually spend the day isolating intestinal epithelial cells from mice or performing cell culture-related work, but there are also days which I spend entirely in front of the computer, analysing my data or catching up on novel publications online. I studied Biochemistry at the University of Bristol
It was absolutely brilliant!
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