When the term second cancer is used, it usually refers to a second primary cancer, in other words, a different cancer than the first cancer, arising in a different organ or tissue.
Your doctor might consider your risk factors, symptoms, and results from exams, imaging tests and pathology tests when trying to determine where your cancer began.Signs and symptoms of carcinoma of unknown primary depend on what part of the body is involved. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Cancer.Net. Secondary Lung Cancer: What's the Difference?What is a Metastasis and Why, How, and Where Do They Happen?How Cancer Spreads to the Lungs and What It Means for the PatientWhat Do You Mean You Don't Know What Kind of Cancer I Have?What Are Secondary Cancers in People With Hodgkin Disease?10 Rational Reasons to Stop Smoking After a Diagnosis of CancerPrimary and Metastatic - Differences Between Brain Cancer vs. TumorsWhat Kind of Cancer Did Lance Armstrong Have and How Did He Survive?Breast Cancer Screening for Childhood Cancer Survivors The most common sites in which cancer develops include: Limiting processed foods and red meats can help ward off cancer risk. Ⓒ 2020 About, Inc. (Dotdash) — All rights reservedPrimary vs. In this case, however, the cells would all be lymphoma cells under the microscope such that if cancer cells in the stomach were lymphoma cells, it would be part of the primary cancer, but if they were stomach cells, it would be considered a second primary cancer.
Cancers do not always have a primary site. When this happens, the abnormal cells accumulate and form a tumor. Yet while the primary site where a lymphoma begins may not be known, it is not considered to be a cancer of unknown origin. Read our
Sign up and get your guide!American Society of Clinical Oncology. In contrast, a second or secondary cancer may be defined in a few ways; as either a new primary cancer in another region of the body or as metastasis (spread) of the original primary cancer to another region of the body. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). The distinction between primary and secondary cancer can make a significant difference in treatment options and approaches. As noted above, primary cancer refers to the initial cancer a person experiences, whether that is lung cancer, breast cancer, or another type of cancer. Cancer Types by Site.
In some cases, the original site where a cancer starts is unknown, and doctors may be uncertain if a cancer that is diagnosed is secondary cancer (metastasis) from a cancer that hasn't yet been found, or instead of a primary cancer. A single copy of these materials may be reprinted for noncommercial personal use only. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
By using Verywell Health, you accept our With Hodgkin disease, the treatment of the disease which is often at a young age combined with a high survival rate is associated with a high risk of secondary cancers. Cancer starts when cells begin to grow out of control. The terms second and secondary cancer are sometimes used interchangeably but can mean different things.
Primary cancer is defined as the original site (organ or tissue) where cancer began. For example, cancer that started in the lung and spread to the liver is called lung cancer with spread to the liver, not liver cancer. It's thought that the risk may be as high as 20 percent to 30 percent. Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. Medical professionals frequently refer to cancers based on their histological type. This isn't surprising, as some of the risk factors for cancer, such as smoking, raise the risk of several types of cancer.
All rights reserved. There are also a number of hereditary cancer syndromes that increase the risk of cancer in more than one organ or tissue type.
A 2017 Israeli study found that among breast cancer survivors, 3.6 percent developed a second primary cancer within 5 years of their original diagnosis, and 8.2 percent within 10 years of their diagnosis.
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